Effect of thyme extract supplementation on lipid peroxidation, antioxidant capacity, PGC-1α content and endurance exercise performance in rats

نویسندگانMostafa Khani, Pezhman Motamedi, Mohammad Reza Dehkhoda, Saeed Dabagh Nikukheslat, Pouran Karimi
نشریهJournal of the International Society of Sports Nutrition
نوع مقالهFull Paper
تاریخ انتشار2017/4/21
رتبه نشریهISI
نوع نشریهچاپی
کشور محل چاپبریتانیا

چکیده مقاله

Athletes have a large extent of oxidant agent production. In the current study, we aimed to determine the influence of thyme extract on the endurance exercise performance, mitochondrial biogenesis, and antioxidant status in rats.

Methods

Twenty male Wistar rats were randomly divided into two groups receiving either normal drinking water (non-supplemented group, n = 10) or thyme extract, 400 mg/kg, (supplemented group, n = 10). Rats in both groups were subjected to endurance treadmill training (27 m/min, 10% grade, 60 min, and 5 days/week for 8 weeks). Finally, to determine the endurance capacity, time to exhaustion treadmill running at 36 m/min speed was assessed. At the end of the endurance capacity test, serum and soleus muscle samples were collected and their superoxide dismutase (SOD) and glutathione peroxidase …

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